Ethyl 4-formyl-1H-pyrrole-2-carboxylate

Ethyl 4-formyl-1H-pyrrole-2-carboxylate - Names and Identifiers

Name	Ethyl 4-formyl-1H-pyrrole-2-carboxylate
Synonyms	Ethyl 4-formyl-2-pyrrolecarboxylate Ethyl 4-forMylpyrrole-2-carboxylate ethyl 4-formyl-1H-pyrrole-2-carboxylate Ethyl 4-formyl-1H-pyrrole-2-carboxylate 1H-Pyrrole-2-carboxylic acid, 4-formyl-, ethyl ester 1H-pyrrole-2-carboxylic acid, 4-formyl-, ethyl ester ethyl 4-forMyl-1H-pyrrole-2-carboxylateC8H9NO3 166.15
CAS	7126-57-0
EINECS	1533716-785-6
InChI	InChI=1/C8H9NO3/c1-2-12-8(11)7-3-6(5-10)4-9-7/h3-5,9H,2H2,1H3

Ethyl 4-formyl-1H-pyrrole-2-carboxylate - Physico-chemical Properties

Molecular Formula	C8H9NO3
Molar Mass	167.16
Density	1.249±0.06 g/cm3(Predicted)
Melting Point	101-105℃
Boling Point	126-127 °C(Press: 0.05 Torr)
Flash Point	156.5°C
Solubility	Miscible with ethyl acetate.
Vapor Presure	0.000122mmHg at 25°C
pKa	13.75±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.569

Ethyl 4-formyl-1H-pyrrole-2-carboxylate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	37 - Wear suitable gloves.
WGK Germany	3

Ethyl 4-formyl-1H-pyrrole-2-carboxylate - Introduction

Ethyl is an organic compound with the chemical formula C10H11NO3. It is a yellow to orange solid with an aromatic odor of phenones.

The main use of this compound is as an intermediate in organic synthesis. It can be used in the synthesis of pyrrole compounds and other organic compounds. Because of its ketone and carbonyl functional groups, it can carry out a variety of chemical reactions.

The preparation of Ethyl is generally obtained by redox reaction of formylaniline and ethyl ester. The specific steps include reacting formylaniline decarboxylated by formic acid with ethyl acetate under alkaline conditions, and then performing oxidation-reduction reaction under acidic conditions to finally obtain the target product.

With regard to safety information, Ethyl is generally not significantly hazardous and toxic under normal conditions of use. However, as an organic compound, it is still recommended to follow the safe operating procedures of the chemical laboratory when handling, including wearing appropriate personal protective equipment (such as gloves and glasses) to avoid skin contact and ingestion. At the same time, avoid contact with oxidants and strong acids during storage to prevent dangerous accidents. When handling and disposing of waste, the relevant environmental and legal and regulatory requirements should be observed.

Last Update：2024-04-10 22:29:15